Apatinib plus hormone therapy for advanced breast cancer
Treatments studied
Part of Cancer clinical trials.
This Phase 2 study tests whether apatinib combined with a CDK4/6 inhibitor and hormone therapy can better control advanced hormone receptor–positive, HER2-negative breast cancer. It may help shrink tumors or slow their growth, especially in cases that can’t be fully treated with surgery or radiation.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You’re age 18 to 75
- You have invasive breast cancer that is hormone-receptor positive and HER2-negative
- Your cancer is locally advanced (can’t be treated fully with local surgery/radiation) or has come back/spread (metastatic)
- Your doctor believes you have measurable disease, or bone lesions that can be followed
- You have enough blood, liver, and kidney function for study treatment
- You have not had prior chemotherapy or targeted therapy for metastatic disease
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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