Testing a device to treat fluid overload in heart failure
Part of Heart & circulation clinical trials.
This trial studies a device (the Nephronyx System) used in the hospital to treat worsening heart failure with fluid buildup, especially when diuretics (water pills) aren’t working well. It aims to check the device’s safety and whether it performs as expected to help patients get better.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are currently hospitalized with worsening heart failure that is the main reason for admission
- You have signs of fluid overload (high EVEREST score of 4 or more)
- Your heart’s pumping function is very reduced but still above a cutoff (left ventricular ejection fraction over 15%)
- Your water pills (diuretics) have not worked well enough
- Your blood marker NT-proBNP is above the study’s age-based cutoff
- You do not have any major exclusions like serious infection, severe liver damage, or certain blood/bleeding problems
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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