Clin2
NCT05762952Possibly a fitRecruiting

Dapagliflozin study for heart micro-blood-flow symptoms in women

Myocardial Ischemia

Treatments studied

Part of Heart & circulation clinical trials.

This early-phase study tests whether dapagliflozin can improve tiny blood-vessel function in women who have heart-ache-like symptoms but no major blockage on heart scans. If it works, it may help symptoms related to “microvascular” heart circulation problems.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 1
Enrollment
40 people
Ages
18 years to 99 years
Study type
Interventional

Who can take part

  • You agree to sign a consent form for the study
  • You were referred for heart testing (catheterization or coronary CT) because of possible reduced blood flow within the last 2 years
  • Your heart scans show no major artery blockage (and blood-flow measures are not in the high-risk range), or you can do a CT scan to confirm this
  • Your kidney function is at least moderate (estimated filtration rate 30 or higher)
  • If you have type 2 diabetes, your diabetes clinician approves the study plan

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT06600178Recruiting· Phase 1
Heart medication for women with chest pain and small vessel disease

This trial tests a diabetes medication called SGLT2 inhibitors to see if it can improve blood flow to the heart and reduce chest pain in women who have small vessel heart disease (microvascular dysfunction) but not blocked large arteries. Participants will take the medication and be monitored for symptom relief and heart function improvements.

Charlottesville, Virginia
NCT07741890Not yet recruiting· Phase 2
Dapagliflozin for chest pain with non-blocked arteries

This study tests whether a daily pill called dapagliflozin can reduce chest pain and improve blood flow in people who have chest pain but no major blockages in their heart arteries. It may help if your heart's small blood vessels are not working properly.

NCT06286878Recruiting· Phase 2/Phase 3
Dapagliflozin after a heart attack: recovery study

This trial tests whether a diabetes drug called dapagliflozin (also used for heart failure) can help people recover better after a recent heart attack. It's for adults who are already on standard blood thinners and have had a heart attack in the past week.

São Paulo, São Paulo
NCT06762964Recruiting· Phase 2
Dapagliflozin for Failing Fontan Circulation

This study tests whether a medication called dapagliflozin (a pill for heart failure) can help people with a Fontan circulation who feel short of breath. It aims to improve symptoms and quality of life.

Rochester, Minnesota
NCT07403955Not yet recruiting
Dapagliflozin for heart function in acute heart failure

This study tests whether a medicine called dapagliflozin can improve heart function in people hospitalized with acute heart failure. It may help the heart pump more efficiently and improve recovery.

NCT07351643Not yet recruiting· Phase 4
Heart scan study of a diabetes drug for non-diabetic heart attack patients

This trial tests whether a diabetes medication, called an SGLT2 inhibitor, can reduce inflammation around heart arteries in people who have had a heart attack but do not have diabetes. The study uses a special heart scan to look at changes over time.

Shenyang, Liaoning

Hear when a new Myocardial Ischemia trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.