Dapagliflozin for chest pain with non-blocked arteries
Treatments studied
Part of Heart & circulation clinical trials.
This study tests whether a daily pill called dapagliflozin can reduce chest pain and improve blood flow in people who have chest pain but no major blockages in their heart arteries. It may help if your heart's small blood vessels are not working properly.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older.
- You have chest pain, pressure, or shortness of breath with activity.
- You have had a heart test showing that the small blood vessels of your heart are not responding normally (within the last 5 years).
- You do not have significant blockages in your main heart arteries (less than 50% narrowing).
- You are not currently taking a similar medication (SGLT2 inhibitor).
- You do not have diabetes that requires medication, heart failure with preserved pumping function, or certain other heart conditions.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study is looking at what causes chest pain in people whose heart arteries are not blocked, which is called coronary microvascular dysfunction. It uses tests and medicines to better understand the condition, which could help guide more personalized treatment.
This trial tests a diabetes medication called SGLT2 inhibitors to see if it can improve blood flow to the heart and reduce chest pain in women who have small vessel heart disease (microvascular dysfunction) but not blocked large arteries. Participants will take the medication and be monitored for symptom relief and heart function improvements.
This early-phase study tests whether dapagliflozin can improve tiny blood-vessel function in women who have heart-ache-like symptoms but no major blockage on heart scans. If it works, it may help symptoms related to “microvascular” heart circulation problems.
This study tests whether a medication called dapagliflozin (a pill for heart failure) can help people with a Fontan circulation who feel short of breath. It aims to improve symptoms and quality of life.
This study tests whether a medicine called dapagliflozin (usually used for diabetes) can reduce heart tissue changes in people with persistent atrial fibrillation. It is given along with the standard ablation procedure, aiming to improve the heart's electrical health and potentially make the procedure more effective.
This trial tests whether a diabetes drug called dapagliflozin (also used for heart failure) can help people recover better after a recent heart attack. It's for adults who are already on standard blood thinners and have had a heart attack in the past week.
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