NRX-101 for treatment-resistant depression with brain stimulation
Part of Mental health clinical trials.
This program provides access to an investigational medicine called NRX-101 for people with treatment-resistant depression who are also receiving brain stimulation therapy (theta burst TMS). The goal is to see if combining this medicine with TMS can help reduce depression symptoms.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be 18 years or older.
- You must be diagnosed with treatment-resistant depression (depression that hasn't responded to at least one standard antidepressant).
- You must be planning to receive a specific type of brain stimulation called theta burst transcranial magnetic stimulation (TBS) as part of your regular care.
- You must be under the care of a psychiatrist or other qualified mental health prescriber who has agreed to participate in this program and guide your treatment.
- You must not be pregnant or breastfeeding, and if you could become pregnant, you must agree to use effective birth control during the study.
- You must not have certain serious medical conditions (such as unstable heart disease, chronic lung disease, epilepsy, severe kidney or liver problems, or a history of brain injury or stroke).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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