Clin2
NCT05784974Possibly a fitNot yet recruiting

Immunotherapy before surgery for early-stage squamous lung cancer

Lung Cancer

Treatments studied

Part of Cancer, Lungs & breathing clinical trials.

This trial tests a medication called cadonilimab (an immunotherapy drug) given alone before surgery for people with early-stage squamous cell lung cancer that can be removed. The goal is to see if this treatment can help shrink the tumor and improve outcomes after surgery.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 2
Enrollment
37 people
Ages
18 years to 75 years
Study type
Interventional

Who can take part

  • You have a type of lung cancer called squamous cell lung cancer that has not spread too far and can still be removed with surgery.
  • Your cancer must be at stage II or IIIA, meaning it is in the lung or nearby lymph nodes but not elsewhere in the body.
  • You have not had any prior treatment for this cancer yet.
  • You must be in generally good health, able to care for yourself, and have well-functioning organs (like your liver and kidneys).
  • You do not have an active autoimmune disease (like lupus or rheumatoid arthritis) that requires medication, and you have not taken immune-suppressing drugs within the last 14 days.
  • You should not have had any other cancer within the past 5 years.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT04286841Recruiting
Immunotherapy before lung surgery for early lung cancer

This trial looks at giving immunotherapy before surgery for certain early-stage lung cancers to help shrink the tumor and improve outcomes. It is mainly for people whose lung cancer can be removed by surgery and who don’t have specific gene changes like EGFR or ALK.

Guangzhou, Guangdong
NCT06492421Recruiting· Phase 2
Immunotherapy before surgery for lung cancer

This trial tests whether giving two immunotherapy drugs directly into the tumor before surgery can shrink non-small cell lung cancer and improve outcomes. It is for people with early-stage (IIIA) lung cancer who are candidates for surgery.

Guanzhou, Guangdong
NCT06532591Recruiting· Phase 2
Cadonilimab plus chemo before and after lung cancer surgery

This trial tests a new immunotherapy drug (cadonilimab) combined with standard chemotherapy, given before and after surgery for lung cancer that has very low PD-L1. The goal is to see if this combination helps shrink the tumor and prevents it from coming back.

Chengdu, Sichuan
NCT06426797Not yet recruiting· Phase 2
Combination treatment before surgery for esophageal cancer

This trial is testing a combination of two drugs (cadonilimab and anlotinib) given before surgery for a type of esophageal cancer called squamous cell carcinoma. The goal is to see if this approach can shrink the tumor and improve surgical outcomes.

NCT06467500Recruiting· Phase 2
Cadonilimab plus chemo for lung cancer after immunotherapy

This trial tests a new drug called cadonilimab combined with chemotherapy for people with advanced lung cancer who have already tried and failed immunotherapy. It aims to see if this combination can help when standard immunotherapy no longer works.

Yichang
NCT07263919Recruiting· Phase 2
Chemo plus cadonilimab before surgery for esophageal cancer

This trial tests adding cadonilimab to standard chemotherapy before surgery for esophageal cancer that can be removed. It aims to see if this combination helps shrink the tumor and improve outcomes.

Xi'an

Hear when a new Lung cancer trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.