Clin2
NCT06918132Possibly a fitRecruiting

Cemiplimab and Fianlimab before lung cancer surgery

Lung Non-Small Cell CarcinomaStage IB Lung Cancer AJCC v8Stage II Lung Cancer AJCC v8Stage IIIA Lung Cancer AJCC v8Stage IIIB Lung Cancer AJCC v8

Treatments studied

Part of Cancer, Lungs & breathing clinical trials.

This trial tests whether two immunotherapy drugs (cemiplimab and fianlimab) given before surgery can help treat stage IB to IIIB non-small cell lung cancer. You must have a PD-L1 level of at least 1% and your surgeon must think the tumor can be fully removed.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 2
Enrollment
60 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You are 18 or older.
  • You have stage IB, II, or IIIB (N2) non-small cell lung cancer confirmed by biopsy.
  • Your cancer has at least 1% PD-L1 (a protein that helps some immunotherapies work).
  • Your surgeon believes the whole tumor can be removed with surgery.
  • You have not had prior chemotherapy, radiation, or immunotherapy for this lung cancer.
  • You do not have certain gene mutations (EGFR, ALK, ROS1) or active autoimmune disease.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07720167Not yet recruiting· Phase 2
Cemiplimab before surgery for early-stage lung cancer

This trial tests whether giving the drug cemiplimab before surgery can help treat early-stage non-small cell lung cancer. The goal is to see if it shrinks the tumor or improves outcomes when followed by standard surgery.

Charleston, South Carolina
NCT06743581Recruiting
Cemiplimab and dupilumab before lung cancer surgery

This study tests two drugs, cemiplimab and dupilumab, given before surgery for early-stage non-small cell lung cancer. The goal is to see if these drugs can shrink the tumor and improve outcomes.

Montreal, Quebec
NCT06865339Recruiting· Phase 2
Radiation plus immunotherapy for advanced lung cancer

This trial tests whether adding two immunotherapy drugs (cemiplimab and fianlimab) to standard radiation and chemotherapy can help treat locally advanced non-small cell lung cancer that hasn't been treated before.

The Bronx, New York
NCT07450183Not yet recruiting· Phase 2
Immunotherapy before and after surgery for early lung cancer

This trial tests a drug called cemiplimab, which helps your immune system fight cancer. It is given before and after surgery to try to reduce the chance of the cancer coming back.

Detroit, Michigan
NCT06088771Recruiting· Phase 1/Phase 2
Study of dupilumab and cemiplimab before lung cancer surgery

This study tests two drugs, dupilumab and cemiplimab, given before surgery for early-stage lung cancer. The goal is to see if these immune-boosting medicines can shrink the tumor and improve outcomes.

New York, New York
NCT06449313Recruiting· Phase 2
Immunotherapy before lung cancer surgery for stage 3 disease

This trial tests whether giving chemotherapy plus immunotherapy before surgery can help shrink stage 3 lung cancer and improve outcomes. The goal is to make the tumor easier to remove and possibly lower the chance of it coming back.

Washington D.C., District of Columbia

Hear when a new Stage IB Lung Cancer AJCC v8 trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.