Clin2
NCT05797558Possibly a fitRecruiting

Medication versus surgery for one-sided adrenal hormone problem

Primary Hyperaldosteronism Due to Adrenal Adenoma

Treatments studied

Part of Hormones & metabolism clinical trials.

This trial compares two ways to treat unilateral primary aldosteronism: taking mineralocorticoid receptor antagonist (MRA) pills or having minimally invasive surgery. It may help decide which option works best and is safest for people who can choose surgery.

Summary written for real people, not researchers, by Clin2.

Phase
N/A
Enrollment
80 people
Ages
18 years to 70 years
Study type
Interventional

Who can take part

  • You have confirmed one-sided primary aldosteronism (unilateral PA)
  • You are between 18 and 70 years old
  • Your doctor believes you could safely have surgery
  • You have no major reasons you can’t have minimally invasive surgery or take MRA tablets
  • You can understand the study information and sign written consent

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT06513585Recruiting
Two treatments for primary aldosteronism: embolization vs. surgery

This study compares two treatments for primary aldosteronism (a condition causing high blood pressure due to an adrenal gland issue). One treatment is a minimally invasive procedure called superselective embolization, and the other is keyhole surgery. This trial aims to see which is better and safer for patients.

Ürümqi, Xinjiang
NCT07558811Not yet recruiting· Phase 4
Steroid therapy after adrenal surgery for kidney health

This study tests whether taking a steroid (hydrocortisone) after adrenal gland surgery helps protect kidney function in people with primary aldosteronism and chronic kidney disease. It could slow down further kidney damage.

NCT07297745Recruiting
Guiding curative treatment for primary aldosteronism with a hybrid steroid

This trial tests whether a special type of steroid medicine can help guide treatment for primary aldosteronism, a condition that causes high blood pressure. If the tests show the problem is in one adrenal gland, you might be able to have surgery to cure it.

Singapore, Singapore
NCT05501080Recruiting
Testing a hormone treatment to improve heart changes in PA

This trial tests whether a treatment called SAAE can improve “ventricular remodeling,” meaning changes in the heart muscle, in people with primary aldosteronism (PA). It may help the heart work more efficiently by targeting the cause of high aldosterone levels.

Nanchang
NCT05368090Recruiting
Ultrasound-guided ablation for primary aldosteronism

This trial studies whether a procedure called endoscopic ultrasound–guided radiofrequency ablation can treat primary aldosteronism (a hormone condition that can raise blood pressure and potassium issues). It may help shrink an overactive adrenal growth and reduce the need for surgery for some people.

Bergen
NCT07470580Recruiting
Heat treatment vs surgery for adrenal gland tumor

This study compares two treatments for a certain type of adrenal gland tumor (Conn's adenoma) that causes high blood pressure. One is a heat-based procedure called radiofrequency ablation and the other is surgery to remove the tumor. The goal is to see which is better at controlling blood pressure.

Toulouse

Hear when a new Primary Hyperaldosteronism Due to Adrenal Adenoma trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.