Clin2
NCT07558811Possibly a fitNot yet recruiting

Steroid therapy after adrenal surgery for kidney health

Primary Aldosteronism Due to Adrenal Hyperplasia

Part of Hormones & metabolism clinical trials.

This study tests whether taking a steroid (hydrocortisone) after adrenal gland surgery helps protect kidney function in people with primary aldosteronism and chronic kidney disease. It could slow down further kidney damage.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 4
Enrollment
90 people
Ages
18 years to 75 years
Study type
Interventional

Who can take part

  • You are between 18 and 75 years old.
  • You have primary aldosteronism (a condition where the adrenal glands make too much aldosterone hormone).
  • Your doctor has confirmed the diagnosis with special tests.
  • Imaging and blood sampling show the problem is on one adrenal gland and you are scheduled for surgery to remove it.
  • Your kidney function is moderately reduced (eGFR between 30 and 60) or you have protein in your urine.
  • You have not used hydrocortisone in the last 3 months.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT06955286Recruiting
Adrenal insufficiency after adrenal surgery in aldosteronism patients

This study looks at how often adrenal insufficiency happens after surgery for primary aldosteronism, especially in patients who also have an overproduction of cortisol. It helps doctors understand if extra hormone support is needed after surgery.

Chongqing, Chongqing Municipality
NCT05797558Recruiting
Medication versus surgery for one-sided adrenal hormone problem

This trial compares two ways to treat unilateral primary aldosteronism: taking mineralocorticoid receptor antagonist (MRA) pills or having minimally invasive surgery. It may help decide which option works best and is safest for people who can choose surgery.

Gothenburg
NCT06513585Recruiting
Two treatments for primary aldosteronism: embolization vs. surgery

This study compares two treatments for primary aldosteronism (a condition causing high blood pressure due to an adrenal gland issue). One treatment is a minimally invasive procedure called superselective embolization, and the other is keyhole surgery. This trial aims to see which is better and safer for patients.

Ürümqi, Xinjiang
NCT07558135Not yet recruiting
Steroid replacement after adrenal gland surgery

This study compares two ways of giving steroid medicine after surgery to remove one adrenal gland. The goal is to find out which approach better protects patients from a condition where the body doesn't make enough steroid hormones.

NCT06513676Recruiting
Adrenal artery treatment for aldosteronism study

This study tests a procedure that blocks tiny arteries in the adrenal gland to treat high blood pressure and low potassium caused by aldosteronism. It may be an option if you cannot take medications or cannot have surgery.

Ürümqi, Xinjiang
NCT05501080Recruiting
Testing a hormone treatment to improve heart changes in PA

This trial tests whether a treatment called SAAE can improve “ventricular remodeling,” meaning changes in the heart muscle, in people with primary aldosteronism (PA). It may help the heart work more efficiently by targeting the cause of high aldosterone levels.

Nanchang

Hear when a new Primary Aldosteronism Due to Adrenal Hyperplasia trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.