Clin2
NCT05798845Possibly a fitRecruiting

Toripalimab plus radiation before surgery for stage II–IIIA lung cancer

NSCLC

Treatments studied

Part of Cancer, Lungs & breathing clinical trials.

This trial studies whether adding toripalimab (an immunotherapy medicine) to radiation can improve outcomes for people with operable stage II to IIIA non-small cell lung cancer. It’s designed for cancers that can be fully removed with surgery, and it aims to see if this combination helps more than radiation alone/standard care.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 2
Enrollment
124 people
Ages
18 years to 75 years
Study type
Interventional

Who can take part

  • You are 18 to 75 years old.
  • Your lung cancer has been confirmed by pathology (biopsy or surgery sample).
  • Your cancer stage is operable stage II–IIIA (or T3N1M0) with no distant spread on CT or PET/CT.
  • Your tumor does NOT have common driver gene changes in EGFR, ALK, or ROS1.
  • You are well enough for treatment and surgery (ECOG 0–1) and have acceptable blood counts, liver, kidney, and heart/lung function.
  • You can provide enough tumor tissue for biomarker testing and you sign the consent form.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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