Stopping hydroxychloroquine in older adults with stable lupus
Treatments studied
Part of Immune system & allergy, Skin clinical trials.
This study looks at whether it is safe for people aged 55 and older with long-standing, stable lupus to stop taking hydroxychloroquine (a medicine that helps control lupus) without their disease flaring up. If you have been taking this medicine for at least 7 years and your lupus has been quiet for a while, you may be able to join.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are at least 55 years old.
- You have had lupus for at least 7 years and your disease is currently not active (your doctor confirms you are in remission).
- You have been taking hydroxychloroquine (Plaquenil) by mouth at least 200 mg every day for at least 7 years.
- You are not on immunosuppressant drugs (like methotrexate or mycophenolate) or biologic medicines (like rituximab or belimumab).
- If you take prednisone, it must be at a dose of 5 mg or less per day, and you have not had a lupus flare in the past year.
- Your eyes were checked recently (within 6 months) for any signs of hydroxychloroquine-related damage.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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