Check if a patient’s own valve tissue can be safely used
Part of Genetic & congenital, Heart & circulation clinical trials.
This study tests whether a new type of heart valve made from your own tissue (an “autologous” valve) can be placed through a catheter safely in adults with leaking and pressure-related problems in the lung heart valve area. If it works well, it could offer a safer option for people who need treatment for pulmonary valve problems.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older
- Doctors must be able to use enough suitable body tissue for the valve (often from the pericardium; other approved tissue sites may work)
- Heart scans (echocardiogram and/or heart MRI) show specific lung valve measurements, such as significant leaking, high pressure/gradient across the valve area, and/or specific right-heart weakness or enlargement
- Your right heart pumping function is reduced (right ventricular ejection fraction under 40%) or your right heart size is high (right ventricular end-diastolic volume over 150 ml/m²)
- You can sign written consent before any study procedures start
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
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This study tests an early, first-use version of a new pulmonary valve device for children whose own valve is not working well. It may help improve blood flow from the heart to the lungs and aims to learn how safe and effective the valve is over time.
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This study looks at a new device called the PULSTA Transcatheter Pulmonary Valve, which is placed without open-heart surgery to help people with a leaky or narrowed pulmonary valve. It aims to see how well the valve works over time.
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