Knee realignment surgery with donor meniscus transplant
Part of Bones, joints & muscles clinical trials.
This trial studies whether combining knee bone realignment surgery (osteotomy) with a donor meniscus transplant can improve knee pain and function in people with arthritis from uneven leg alignment. You would need to commit to physical therapy and repeat checkups with X-rays and MRI scans.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You’re between 20 and 60 years old.
- Your knee arthritis is in one compartment, and it’s not too advanced (Kellgren-Lawrence grade 3 or less).
- Your legs are misaligned enough that a corrective osteotomy is recommended (over 5°).
- The affected knee compartment has a missing or damaged meniscus for the overloaded area.
- You can and agree to follow the rehab plan and return for X-rays and MRI scans.
- You can sign informed consent and fully take part in study visits.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study tests how well a realignment surgery (osteotomy) works for people with mild knee arthritis and a bent knee that's at least 3 degrees off center. The surgery may also fix other knee problems like a torn meniscus or ligament at the same time.
This trial compares two computer-assisted surgical methods for realigning the shinbone (high tibial osteotomy) to treat inner-knee arthritis. It aims to find which technique gives better results for pain and function.
This study looks at how well the kneecap joint holds up many years after a knee realignment surgery (high tibial osteotomy) for inner knee arthritis. If you had this surgery more than 5 years ago, you may be able to join a long-term checkup that uses X-rays and medical records to see how your knee is doing.
This trial tests a surgical procedure that replaces a damaged meniscus (the knee's cushion) while also repairing the ACL (a key ligament), using a tendon graft to stabilize the knee. It is designed for people whose knee problems have not gotten better with therapy or pain relievers.
This study compares two surgical methods for correcting a bow-legged knee caused by arthritis. Both methods aim to realign the knee to reduce pain and improve function, and the trial will see which approach gives better results.
This trial tests a new surgical approach for a specific type of meniscus tear (the cartilage that cushions the knee) in people who have a mild bow-legged (varus) knee. It combines a small bone cut near the knee with arthroscopic repair to fix the tear.
Hear when a new Malalignment, Bone trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.