Interferon gamma for ventilator pneumonia in ICU
Part of Infections, Injuries & trauma, Lungs & breathing clinical trials.
This trial tests whether a medicine called interferon gamma can improve outcomes in adults with a first episode of pneumonia that develops after being on a ventilator in the ICU. It is designed for specific ICU timing, infection severity, and immune marker levels, and it compares treatment on top of standard care.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Be an adult currently in the ICU
- Be on a breathing machine (mechanical ventilation) for more than 5 days
- Have a first-time ventilator-acquired pneumonia episode with CPIS score over 6
- Start antibiotics for this pneumonia within the last 24 hours (and be able to start the study dose within 48 hours)
- Have immune test result: monocyte HLA-DR less than 8000 AB/C
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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