Clin2
NCT05856136Possibly a fitRecruiting

Study how opioid exposure affects diaphragm muscle function

Respiratory Function LossRespiratory Complication

Treatments studied

Part of Lungs & breathing clinical trials.

This study looks at whether receiving opioids for pain during lower-leg surgery changes how well the diaphragm muscle (the main breathing muscle) works afterward. It compares breathing muscle function in people who do and do not have certain lung conditions.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 4
Enrollment
69 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You must be an adult who is having lower-leg (lower extremity) orthopedic surgery at the study hospitals
  • You must be willing to participate in the research study
  • You cannot be pregnant
  • You must not have known lung problems like COPD or asthma that need regular treatment

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07227389Recruiting
Opioid Timing and Breathing Risk After Surgery

This study looks at when opioids are given during surgery and how it affects breathing problems after surgery. It might help understand how to make pain control safer.

Detroit, Michigan
NCT07435337Recruiting· Phase 4
Pain medicine study for heart surgery patients

This trial tests two different pain medicines, nalbuphine and fentanyl, to see which one causes fewer changes in blood pressure and heart rate during the placement of a breathing tube for heart surgery.

Rawalpindi, Punjab Province
NCT06403540Recruiting
Pain relief after belly surgery and diaphragm function

This study looks at how different pain relief methods after major abdominal surgery affect the diaphragm, a muscle that helps you breathe. It may help doctors choose the best way to manage pain while protecting your breathing.

Istanbul
NCT03667027Recruiting
Study of breathing muscle and lung changes during transplant planning

This trial studies how the diaphragm (your main breathing muscle) and lung/airway tissue behave in people who are being supported until they can get a lung transplant. The results may help doctors better understand breathing failure and improve transplant care.

Toronto
NCT05906030Recruiting
Ultrasound to study diaphragm function around surgery

This trial uses ultrasound (a non-painful scanning method) to measure how well the diaphragm works around the time of surgery. It aims to learn whether diaphragm changes during surgery relate to breathing problems, especially in people undergoing abdominal, pelvic, or vascular operations.

Stockholm, Stockholm County
NCT07018375Recruiting· Phase 4
Oliceridine for pain after lung surgery

This study tests a new pain medication called oliceridine given through an IV after lung surgery to see if it helps reduce long-term pain. Participation may help improve pain management after surgery.

Baoding, Hebei

Hear when a new Respiratory Function Loss trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.