Registry of best medication dose adjustment for acute heart failure
Part of Heart & circulation clinical trials.
This study is testing different ways to safely increase the doses of standard heart failure medicines while you are still in the hospital. The goal is to find the best strategy to help your heart work better before you go home.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are currently in the hospital for acute heart failure and have been there for more than 3 days.
- Your blood pressure and heart rate are within a safe range, and your potassium level is not too high.
- You have a high level of a heart stress marker (NT-proBNP), indicating heart failure.
- You are not currently taking full doses of key heart failure medications (or you are on no dose or a low dose of them).
- You have not had a recent heart attack, heart surgery, or heart procedure in the last month, and your kidney function is not severely reduced.
- You are not already enrolled in another heart failure clinical study that requires extra visits.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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This trial tests a new, faster way to increase heart failure medications during a hospital stay, aiming to get patients on the right doses sooner. It is for people with weak heart pumping (ejection fraction 40% or less) who are currently in the hospital for heart failure and are on low doses of standard medications.
This trial tests whether safely increasing the dose of standard heart failure medications can improve outcomes in people with a weak heart pump, while keeping a close eye on kidney function. It may be a good fit if you have heart failure with reduced ejection fraction and are not yet on the highest recommended doses of your medicines.
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