Clinical trials
Acute Heart Failure clinical trials
Below are recruiting acute heart failure clinical trials, each written for real people, not researchers. We’re tracking 436 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06736574RecruitingPhase 3
Study of omecamtiv mecarbil for chronic heart failure with very weak heart pump
This study tests an investigational medicine (omecamtiv mecarbil) for people with chronic heart failure and very low pumping strength. It looks at whether the drug can help prevent heart failure events or the need for stronger treatments.
Alexander City, AlabamaAges 18–85 - NCT07038356RecruitingPhase 3
Continuing empagliflozin during heart failure hospitalizations
This study tests whether continuing empagliflozin (a heart failure medicine) during a hospital stay for heart failure is beneficial compared to stopping it. Participation may help improve recovery and reduce complications.
Jena, ThuringiaAges 18 years+ - NCT05677100Recruiting
Aortix device for acute heart failure
This trial is testing a small pump placed in the aorta to help the kidneys remove extra fluid when standard IV diuretics aren't working well enough for severe heart failure. It may help you if you're hospitalized and still very congested (swollen, fluid buildup) despite strong water pills.
Phoenix, ArizonaAges 21 years+ - NCT05585125RecruitingPhase 4
Testing an informed approach for older adults with HFpEF
This study looks at an “informed” approach to help manage HFpEF (a type of heart failure) in people age 65 and older. It checks whether a structured plan and monitoring are practical and safe for you over time.
New York, New YorkAges 65 years+ - NCT07547540RecruitingPhase 1
Study of an investigational drug for heart failure
This study tests an experimental drug called LY3971297 to see if it can help people with chronic heart failure. It aims to find out if the drug is safe and if it improves heart function.
Detroit, MichiganAges 18–65 - NCT06469814Enrolling by invitation
Heart failure snapshot study
This study is a snapshot of patients with heart failure and aims to better understand how heart failure is managed in different settings, from outpatient care to emergency treatment.
YerevanAges 18 years+ - NCT07232030Recruiting
Barostim device for heart failure treatment
This trial tests a device called Barostim, which is implanted under the skin to stimulate nerves that help control heart failure. It's for people with mild to moderate heart failure whose symptoms are not fully controlled by medications.
Mobile, AlabamaAges 18 years+ - NCT06800716Recruiting
Impella temporary pump for end-stage heart failure
This study tests whether using a temporary heart pump called Impella 5.5 can help strengthen a very weak and enlarged heart (dilated cardiomyopathy) in people who are waiting for a heart transplant. If you qualify, the pump is placed to support your heart temporarily, and the research team will check how your heart responds.
New York, New YorkAges 18 years+ - NCT07218627RecruitingPhase 1
Study of an investigational medicine for heart failure
This study tests an experimental medicine called NNC0537-1482 for people with heart failure. It aims to see if the medicine helps improve symptoms and heart function.
LondonAges 40–75 - NCT05276219RecruitingPhase 4
Vasodilators or diuretics for acute heart failure
This trial compares two treatments for sudden heart failure symptoms like severe shortness of breath. It aims to see whether opening blood vessels or using a water pill works better to relieve congestion and improve breathing.
Copenhagen, CopenhagenAges 18 years+ - NCT07251894Enrolling by invitation
Meals after heart failure hospitalization
This study provides medically tailored meals to people recently hospitalized with heart failure to see if they help recovery. It is testing whether having healthy meals delivered can improve how patients feel and reduce the chance of being readmitted to the hospital.
Philadelphia, PennsylvaniaAges 18 years+ - NCT06310031Recruiting
Testing BrioVAD heart pump for severe heart failure
This trial tests a new left-ventricular assist device (LVAD) called BrioVAD for people with advanced heart failure who are not getting enough benefit from medicines. If you qualify, the device is implanted to help your heart pump blood.
Birmingham, AlabamaAges 18–100 - NCT06166654RecruitingPhase 4
Better water pill therapy for acute heart failure
This trial tests different water pill (diuretic) strategies for people hospitalized with acute heart failure and too much fluid. It is designed for patients who may not respond well to standard water pills, to find a more effective way to relieve symptoms.
Hvidovre, Capital Region of DenmarkAges 18 years+ - NCT07397650RecruitingPhase 4
Early finerenone for heart failure in hospital
This trial tests if starting finerenone early helps patients hospitalized with heart failure who have symptoms like shortness of breath or swelling. It aims to see if the drug is safe and effective when given soon after admission.
Handa, Aichi-kenAges 18 years+ - NCT06465498Recruiting
Lung ultrasound for heart failure congestion treatment
This trial tests whether using lung ultrasound to guide decongestion treatment improves outcomes for patients hospitalized with congestive heart failure. It may help doctors tailor your care more precisely.
Geneva, Canton of GenevaAges 18 years+ - NCT03806972Recruiting
Study outcomes after emergency heart failure admission
This study follows people admitted to the emergency department for acute heart failure to understand their short- and long-term outcomes. It may help doctors predict who needs more support and improve follow-up after discharge.
Monastir, Monastir GovernorateAges 18–80 - NCT06967441Recruiting
Respiratory viruses and acute heart failure study
This trial looks at whether a respiratory virus might be triggering your heart failure. It will test your nasal swab for viruses to help doctors understand and treat your condition better.
Seongnam-si, Gyeonggi-doAges 19 years+ - NCT06656832Recruiting
How Heart Failure Progresses in Hospitalized Patients
This study looks at why heart failure gets worse over time. It involves people who have been hospitalized for heart failure and have a known heart abnormality. Doctors will monitor your health to find clues about disease progression.
LeipzigAges 18 years+ - NCT06783166RecruitingPhase 2/Phase 3
Comparing two medications for acute heart failure with fluid buildup
This trial tests if dapagliflozin or acetazolamide works better for people hospitalized with heart failure who have extra fluid in their body (congestion). The study will compare how well each medication helps remove fluid when used with standard IV diuretics.
Al MansurahAges 18 years+ - NCT05255172Enrolling by invitation
Exercise program for heart failure with preserved or reduced pumping
This trial tests whether a structured exercise program can help people with heart failure. It focuses on people who are currently not very active, aiming to improve symptoms and heart/fitness measures safely.
LundAges 50–90 - NCT05392764RecruitingPhase 3
SGLT2 medicine for high-risk people after sudden worsening heart failure
This Phase 3 trial tests whether starting an SGLT2 inhibitor early in the hospital can improve outcomes for people at high risk after acute (sudden) heart failure. If you qualify, you would be randomized to receive the study medicine or standard care, started within 12 hours of admission.
Anjo, Aichi-kenAges 20 years+ - NCT04441203Recruiting
Virtual clinic for managing heart failure at home
This trial tests a virtual “heart failure clinic” and home heart monitoring to help people manage symptoms and outcomes. It may help by catching problems earlier and guiding safer self-care between doctor visits.
Montreal, QuebecAges 18 years+ - NCT02444416Recruiting
Registry study for people with new acute heart failure
This study is a registry that collects information about people who come to care with sudden (acute) worsening heart failure symptoms. If your test shows a higher BNP level, your doctors may use your details to better understand and track acute heart failure care.
GenevaAges 16–100 - NCT04343430Recruiting
Hospital study for fluid buildup in heart failure with preserved heart function
This study looks at how well doctors can assess fluid buildup before you leave the hospital if you have a type of heart failure called “preserved ejection fraction.” It may help improve decisions about when and how safely people are discharged.
Vandœuvre-lès-NancyAges 18 years+
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Common questions
- Are there clinical trials for acute heart failure?
- Yes. Clin2 currently lists 436 recruiting acute heart failure studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a acute heart failure trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a acute heart failure trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.