Clin2
NCT05874570Possibly a fitRecruiting

Doxycycline for H. pylori after prior treatment failure

Helicobacter Pylori Infection

Treatments studied

Part of Digestive system, Infections clinical trials.

This trial tests whether doxycycline can “rescue” or improve treatment for an H. pylori infection that has already not responded to previous therapy. It may help people whose stomach infection keeps coming back or never cleared.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 4
Enrollment
368 people
Ages
18 years to 70 years
Study type
Interventional

Who can take part

  • You must be able and willing to join the study and sign informed consent
  • You must have a confirmed H. pylori infection that did not clear after prior treatment
  • You must be between 18 and 80 years old
  • You must not have had stomach surgery that removes part of your stomach (gastrectomy)
  • You must not be pregnant or breastfeeding
  • You must not have taken antibiotics, bismuth, acid-suppressing medicines, or Chinese herbal medicine in the past 8 weeks

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT05061732Recruiting· Phase 4
Treatment and follow-up study for Helicobacter pylori infection

This trial studies how to eradicate Helicobacter pylori (a germ in the stomach) and monitor follow-up results after treatment. You may be a candidate if you have confirmed infection and have not taken certain stomach medicines or antibiotics recently.

Shanghai, Shanghai Municipality
NCT05332444Recruiting· Phase 4
Check if stomach-bacteria testing improves rescue treatment for H. pylori

This study compares two ways to treat Helicobacter pylori (H. pylori) infection that didn’t go away with prior therapy. One approach uses test results to guide which medicines to use, and the other uses standard (“empiric”) treatment. The goal is to see which works better and more safely as a rescue plan.

Taipei
NCT06561698Recruiting· Phase 4
High-dose dual therapy vs minocycline quadruple therapy for H. pylori

This trial compares two treatments for H. pylori infection: a high-dose two-drug regimen and a four-drug regimen containing minocycline. It aims to find which is more effective and better tolerated.

Hebi, Henan
NCT07729293Not yet recruiting
Pylori Duo for new H. pylori infection treatment

This trial tests a treatment called Pylori Duo for people newly diagnosed with H. pylori infection. It aims to both treat the infection and prevent it from coming back.

Don Benito, Badajoz
NCT07746934Not yet recruiting
Comparing two antibiotic combinations for H. pylori infection

This trial tests two different antibiotic combinations (both including bismuth) to see which works better at getting rid of an H. pylori infection in the stomach. The goal is to find a more effective way to clear the infection and reduce stomach problems.

Ho Chi Minh City, Ho Chi Minh
NCT07358130Recruiting
Comparing two treatments for H. pylori infection

This trial tests two different ways to treat Helicobacter pylori (H. pylori), a bacteria that can cause stomach ulcers. One treatment combines three medicines (bismuth, amoxicillin, and vonoprazan), and the other uses four medicines (bismuth quadruple therapy). The goal is to see which works better.

Kaohsiung City

Hear when a new Helicobacter Pylori Infection trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.