Doxycycline for H. pylori after prior treatment failure
Part of Digestive system, Infections clinical trials.
This trial tests whether doxycycline can “rescue” or improve treatment for an H. pylori infection that has already not responded to previous therapy. It may help people whose stomach infection keeps coming back or never cleared.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be able and willing to join the study and sign informed consent
- You must have a confirmed H. pylori infection that did not clear after prior treatment
- You must be between 18 and 80 years old
- You must not have had stomach surgery that removes part of your stomach (gastrectomy)
- You must not be pregnant or breastfeeding
- You must not have taken antibiotics, bismuth, acid-suppressing medicines, or Chinese herbal medicine in the past 8 weeks
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study compares two ways to treat Helicobacter pylori (H. pylori) infection that didn’t go away with prior therapy. One approach uses test results to guide which medicines to use, and the other uses standard (“empiric”) treatment. The goal is to see which works better and more safely as a rescue plan.
This study is testing whether giving H. pylori treatment based on the specific bacteria found in your stomach works better than the standard one-size-fits-all approach. If you are already getting an endoscopy with a biopsy, this trial could help find the most effective medication for your infection.
This trial tests two different ways to treat Helicobacter pylori (H. pylori), a bacteria that can cause stomach ulcers. One treatment combines three medicines (bismuth, amoxicillin, and vonoprazan), and the other uses four medicines (bismuth quadruple therapy). The goal is to see which works better.
This study compares two different antibiotic combinations (metronidazole vs. tinidazole, both with bismuth and other medicines) to see which works better at getting rid of H. pylori, a bacteria that can cause stomach ulcers. If you have H. pylori and haven't been treated before, you may be able to help us find the best option.
This study tests a new treatment called Pylori Duo, used along with standard care, to help get rid of H. pylori bacteria in the stomach and stop it from coming back. It may be a good option if you are newly diagnosed and haven't been treated before.
This trial tests a new two-step antibiotic treatment for adults with chronic gastritis caused by H. pylori bacteria. If you have not been treated for H. pylori before and are between 18 and 70, you may be able to join.
Hear when a new Helicobacter Pylori Infection trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.