Pioglitazone for aortic valve disease
Part of Heart & circulation clinical trials.
This study tests whether pioglitazone, a medicine commonly used for diabetes, can slow the worsening of a condition called calcific aortic valve disease, where calcium builds up on the heart's aortic valve. It may help patients with mild to moderate valve narrowing avoid the need for surgery.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 35 years or older
- You have been diagnosed with mild to moderate aortic valve narrowing, confirmed by an echocardiogram (ultrasound of the heart)
- Your heart valve calcium score is at least 200 units, as seen on a CT scan
- You have not had surgery on your aortic valve before
- You have not been diagnosed with pancreatitis (inflammation of the pancreas) or cancer recently
- You are not pregnant or breastfeeding
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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