Vericiguat for slowing aortic valve calcium buildup
Treatments studied
Part of Heart & circulation clinical trials.
This trial tests if the drug vericiguat can slow down the buildup of calcium in the aortic valve, which causes it to narrow and stiffen. If you have mild-to-moderate aortic valve stenosis and meet the other criteria, this study may help protect your valve from getting worse.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 35 and 79 years old.
- Your aortic valve stenosis is mild to moderate on an echocardiogram.
- A CT scan shows a certain amount of calcium buildup in your valve.
- You are not taking any medications like sildenafil or nitrates.
- You are not planning to have valve surgery or replacement soon.
- Your heart pumps blood well (LVEF 50% or higher) and you are not in advanced heart failure.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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