Testing NY-ESO-1 T-cell therapy for advanced solid tumors
Treatments studied
Part of Cancer clinical trials.
This Phase 1 study tests a personalized immune therapy made from T cells to treat advanced solid cancers that carry a marker called NY-ESO-1. You may be able to join if your tumor shows the right NY-ESO-1 level and your body and lab tests can safely handle treatment.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 70 years old, and you understand and can sign consent.
- Your cancer is a solid tumor that has spread or come back, and it is confirmed by biopsy.
- Your cancer has been tried with standard treatments and is no longer responding (or has progressed).
- Your tumor has NY-ESO-1 on it at the required level (at least 25% positive cells, intensity “++” or higher).
- You have the right blood type marker: HLA-A2, but not HLA-A*0203.
- Your blood, liver, kidney, clotting tests, and heart scan meet the safety thresholds, and you can provide fresh or stored tumor tissue.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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