UniLine heart valve replacement study for aortic or mitral disease
Part of Heart & circulation clinical trials.
This trial studies how well a specific bioprosthetic heart valve (“UniLine”) works after surgery, including safety and how long it lasts. You may be able to join if you are an adult getting a first-time mitral or aortic valve replacement with this exact valve.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older.
- You are having an aortic or mitral valve replacement using the UniLine bioprosthesis.
- You have not had any previous heart valve replacement.
- You should not have any other artificial heart valve in any position.
- You should not have had prior valve repair, or surgery for an ascending aorta aneurysm, or left-ventricle aneurysm surgery.
- You should not have active cancer or a past history of cancer.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study tests a new biological heart valve called 'UniLine' for people who need to replace their mitral valve (the valve between the left heart chambers) or aortic valve (the main valve sending blood to the body) for the first time. If you qualify, you would have planned surgery (not an emergency) and need to be free of certain other serious health conditions.
This trial tests how well a new replacement heart valve works and how safe it is. You might qualify if you need a planned first-time aortic valve replacement and are 60-70 years old (or younger if you cannot take blood thinners).
This study tests a biological (tissue) heart valve replacement system designed to be easier to change later. It may help people who need valve surgery because their valve is narrowed or damaged.
This study tests a new type of prosthetic heart valve made from a special polymer material. It is for adults who need surgical replacement of either the mitral or aortic valve.
This early-stage trial tests a new device called the ReValve System that replaces a damaged mitral valve (the valve that controls blood flow in your heart). The study is for people with a weakened heart who have leaking mitral valves and are experiencing heart failure symptoms.
This study looks at how well a new valve works when placed inside a previous mitral or tricuspid valve repair or replacement. It may help people who need another procedure on these heart valves.
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