First-in-human test of a new TAVR valve for severe aortic narrowing
Part of Heart & circulation clinical trials.
This trial tests a new heart valve replacement (TAVR) system in people with severe, symptomatic aortic stenosis. If you qualify, it may offer a less invasive option compared with open-heart valve surgery, while also helping researchers understand safety and early effectiveness.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You’re at least 18 years old and can understand the study and sign consent
- You have severe aortic stenosis with symptoms (at least NYHA class II)
- Your heart team considers you at intermediate surgical risk or you’re age 75 or older
- CT-based measurements show your aortic valve and surrounding area fit the device size and shape
- Your leg blood vessels (femoral/iliac arteries) are large enough and not too blocked/twisted for a small 12Fr catheter
- You’re likely to be a higher risk for bleeding or vessel complications during access
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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