Compare stool treatment options for repeat C. difficile infection
Treatments studied
Part of Infections clinical trials.
This Phase 1 study tests a stool-based treatment approach for people who keep getting C. difficile diarrhea that returns after antibiotics. The goal is to see whether the treatment is safe and works to stop future episodes.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older and can sign informed consent
- You have had C. difficile (CDI) twice or more in the last 6 months, including this current episode
- Your stool test for toxin-producing CDI is positive within 60 days, and you took standard CDI antibiotics recently
- Your diarrhea improved during the last antibiotic course (no more than 3 unformed stools per day for at least 2 days)
- You can do the planned colonoscopy as an outpatient (not an inpatient at the time of the procedure)
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This Phase 1 study tests whether transferring healthy gut bacteria (a fecal microbiome transplant) can help children with repeated or moderate-to-severe C. difficile infection. It focuses on changing gut bacteria to reduce ongoing infection and symptoms.
This trial studies using a fecal microbiota transplant (FMT)—healthy gut bacteria moved from a screened donor—to help treat recurring or hard-to-control C. difficile infection. It may help restore a healthier gut environment when standard treatments keep failing or the infection returns.
This study looks at how fecal microbiota transplantation (a transplant of healthy gut bacteria) works for people who get C. difficile infection repeatedly. It also focuses on collecting follow-up information to better understand which patients benefit and how.
This Phase 1 study tests defined fecal microbiota (healthy gut bacteria) given to people with C. difficile diarrhea that didn’t go away or came back soon after antibiotics. It may help by restoring a healthier balance of gut bacteria so the infection can stop recurring.
This trial tests whether giving a stool transplant (also called FMT) can treat a new, early C. difficile infection in people who have improved while on antibiotics. It may help some people prevent the infection from coming back or worsening.
This trial studies whether fecal microbiota transplantation (a procedure that transfers healthy stool bacteria) can change a person’s gut bacteria after repeated C. difficile infection. It may help reduce recurring infections by restoring a healthier balance of gut microbes.
Hear when a new Clostridiodies Difficile Infections trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.