Weight loss genetics study with naltrexone and bupropion
Part of Hormones & metabolism clinical trials.
This trial studies how your genetic makeup and body response may affect weight loss with a medication combination called naltrexone and bupropion. If you qualify, you’ll likely take these medicines and be monitored for safety and changes in weight over time.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Be between 18 and 65 years old
- Have a BMI of 30–50, or BMI 27–29.9 with at least one weight-related problem (controlled high blood pressure, cholesterol problems, sleep apnea, or joint arthritis)
- You should not have obesity caused by certain hormone/brain conditions (endocrine or hypothalamic causes)
- You must not have diabetes that’s not controlled (HbA1c above 6.5%)
- You cannot have certain major health or safety issues (heart/stroke, liver/kidney disease, seizure history, serious psychiatric illness, glaucoma, or regular tobacco use)
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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