CPI-0209 plus platinum chemo for recurring ovarian cancer
Treatments studied
Part of Cancer, Hormones & metabolism, Women’s health & pregnancy clinical trials.
This Phase 1 trial tests CPI-0209 combined with the standard platinum chemotherapy approach in people whose ovarian (or related) cancer has returned after prior platinum treatment. The goal is to find a safe dose and see whether this combination can help keep the cancer under control.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Your cancer must have returned more than 6 months after your last platinum chemotherapy (it is “platinum-sensitive”).
- You must have had at least one prior platinum-based treatment line; prior bevacizumab or PARP inhibitor (PARPi) treatment is allowed.
- You must be well enough to participate (ECOG performance status 0 to 2) and expected to live at least 3 months.
- Blood tests and organ function must meet study thresholds (kidney, liver, blood counts, and clotting) or be corrected to acceptable levels before starting.
- You must be able to swallow the study medicine by mouth (tablet or oral liquid).
- If you can become pregnant or father a child, you must use highly effective birth control during the study and for 183 days after stopping. Pregnancy or breastfeeding are not allowed.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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