Clin2
NCT05947344Possibly a fitRecruiting

Testing STI-8591 for advanced acute myeloid leukemia

AML, Adult

Part of Blood & lymphatic, Cancer clinical trials.

This early-stage study tests STI-8591 in people with advanced acute myeloid leukemia (AML) or certain related blood cancers. It mainly aims to find a safe dose and see whether the treatment can work for patients whose disease did not respond to standard care or who cannot get it.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 1
Enrollment
84 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You are at least 18 years old and can sign consent willingly
  • Your expected survival is more than 12 weeks
  • You have advanced AML or related MDS/MPN-related AML that has failed or is intolerant to standard therapy (or you can’t access standard therapy)
  • You are well enough to participate (performance status 0 to 2) and can undergo bone marrow sampling
  • Recent blood and organ tests must be within specific limits (liver, kidney, and blood counts, with some allowances for medicines like hydroxyurea)
  • You can take oral study medicine and agree to follow study visit schedules and safety rules, including pregnancy prevention if applicable

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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