Clin2
NCT05956327Possibly a fitRecruiting

Study physical training to change brain signals in schizophrenia

SchizophreniaNeuronal PlasticityExercise

Part of Mental health clinical trials.

This trial studies whether structured physical training can change brain “signal wiring” in people with schizophrenia. Researchers will also look at related molecular changes to understand why exercise might improve symptoms.

Summary written for real people, not researchers, by Clin2.

Phase
N/A
Enrollment
156 people
Ages
18 years to 65 years
Study type
Interventional

Who can take part

  • You agree to take part and sign informed consent.
  • You have a schizophrenia diagnosis based on standard diagnostic criteria (ICD-10 and DSM-5).
  • Your symptom severity score (PANSS) must be 75 or less before training starts.
  • You must be on a stable schizophrenia treatment plan—your main antipsychotic dose should be unchanged for at least 2 weeks.
  • If you can become pregnant, you must use reliable birth control.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT01392885Recruiting
Brain health and exercise program for schizophrenia

This trial studies how a structured exercise program may affect brain health in people with schizophrenia or schizoaffective disorder. It may help researchers understand whether exercise can support brain function and overall health in this condition.

Vancouver, British Columbia
NCT02455193Recruiting
Exercise study for people with schizophrenia

This study looks at how exercise affects brain function in people with schizophrenia or schizoaffective disorder. It may help researchers understand whether exercise can improve brain-related outcomes alongside standard treatment.

Aurora, Colorado
NCT06482918Recruiting
Cognitive training for schizophrenia: testing brain flexibility

This trial tests a cognitive remediation program to see if it can improve thinking skills in people with schizophrenia. It also looks at how the brain changes with this training.

Santiago, RM
NCT07404319Not yet recruiting
Exercise and brain stimulation for thinking in schizophrenia

This study tests whether aerobic exercise alone, or exercise combined with a gentle brain stimulation technique called tDCS, can improve thinking and memory in people with treatment-resistant schizophrenia.

Hong Kong
NCT07745140Not yet recruiting
Brain stimulation and exercise for thinking skills in schizophrenia

This study combines brain stimulation with physical exercise to see if it can improve thinking and memory in people with schizophrenia. You will get both treatments and be tested on cognitive functions.

Hung Hom, Kowloon
NCT07659938Not yet recruiting
Brain training for schizophrenia using neurofeedback

This trial tests a brain-training technique called neurofeedback, which helps you learn to control certain brainwaves. It might improve thinking and daily function for people with schizophrenia who are otherwise stable.

La Jolla, California

Hear when a new Schizophrenia trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.