Study drug R-2487 for people with active rheumatoid arthritis
Part of Bones, joints & muscles, Immune system & allergy, Skin clinical trials.
This Phase 1 study tests how the drug R-2487 behaves in the body and looks at early safety in adults with active rheumatoid arthritis. If you have ongoing joint inflammation despite standard treatments, this trial may offer a chance to try an investigational therapy under close monitoring.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You’re between 18 and 75 years old, and you can sign informed consent
- You have active rheumatoid arthritis (RA) with enough symptoms for an RA diagnosis, plus joint swelling/tenderness
- At screening you must have a high RA activity score (CDAI > 10) and at least 3 tender and 3 swollen joints (not counting fingertip joints)
- You must be able to stay on certain RA medicines or be “washed out” from some recent RA treatments for the required time
- If you take steroid pills by mouth, your dose must be stable and equivalent to 10 mg prednisone or less per day for at least 4 weeks
- You must be willing to avoid vaccines during the study and use effective birth control if pregnancy is possible
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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