Stem cell injection for active ankylosing spondylitis safety
Treatments studied
Part of Bones, joints & muscles clinical trials.
This Phase 1 study tests how safe and tolerable an injection made from umbilical cord stem cells is for people with active ankylosing spondylitis. It may help doctors learn a new treatment approach and understand side effects in the short term.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have a confirmed diagnosis of ankylosing spondylitis that is currently active (BASDAI score 4 or higher).
- You have tried at least two non-steroid anti-inflammatory medicines (NSAIDs) for a total of 4 weeks or more and either did not improve much or could not tolerate them.
- If you take steroid pills, your dose must be stable for at least 4 weeks and be no more than the equivalent of 10 mg prednisone per day.
- You (and your spouse/partner if applicable) agree to use effective birth control during the study and for 6 months after the last dose (and you do not plan children around screening and early in the study).
- You are willing and able to sign consent and follow study procedures.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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