Stem cell treatment for ankylosing spondylitis
Treatments studied
Part of Bones, joints & muscles clinical trials.
This study tests a new treatment using umbilical cord stem cells given by injection to help reduce inflammation and improve symptoms of ankylosing spondylitis. It is for people who have not gotten enough relief from standard medications, including biologics.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 65 years old.
- You have been diagnosed with ankylosing spondylitis, confirmed by imaging showing sacroiliitis (inflammation of the sacroiliac joints) plus at least one of: back pain that improves with activity, limited spine motion, or reduced chest expansion.
- Your disease is currently active, meaning your BASDAI score is at least 4 or your ASDAS score is at least 2.1.
- You have had an inadequate response to nonsteroidal anti-inflammatory drugs (NSAIDs, like ibuprofen) or cannot take them due to side effects or contraindications.
- You have tried and not adequately responded to at least two biologic medications (like TNF inhibitors or IL-17 inhibitors) or could not tolerate at least one.
- You must be willing to follow the study protocol, including disease education and physical exercise, and avoid pregnancy for at least 6 months after the last dose.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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