Trastuzumab, serplulimab, and chemo after stomach cancer surgery
Treatments studied
Part of Cancer, Digestive system clinical trials.
This Phase 2 study looks at whether adding serplulimab to trastuzumab and chemotherapy after surgery can lower the chance of stomach cancer coming back. It is for people with HER2-positive stage II–III stomach adenocarcinoma who have already had curative surgery with lymph node removal.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 20 and 80 years old
- Your stomach cancer is confirmed as adenocarcinoma and is stage II or III
- You had surgery that fully removed the tumor (R0) and included D2 lymph node removal
- Your tumor is HER2-positive on a tissue test (IHC or FISH)
- Your health and blood counts are strong enough (ECOG 0–1; blood, liver, and kidney tests meet limits)
- You have not had chemotherapy, radiation, immunotherapy, or targeted therapy before joining
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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