Low-dose buprenorphine for pain in opioid-naive adults
Treatments studied
Part of Brain & nervous system, Mental health, Pain clinical trials.
This study tests a low-dose form of buprenorphine (a medicine for pain) placed inside the cheek. It is designed for people who have never taken opioids before, to see how well it works for pain and how likely it is to be misused.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be between 18 and 65 years old.
- You must not have taken any opioid pain medications or buprenorphine in the last 3 months.
- You must be in good general health, with no chronic pain, liver or kidney disease, seizure disorder, or certain psychiatric conditions.
- You must not have a history of substance use disorder.
- You must not be pregnant, and must weigh at least 60 kg (about 132 pounds).
- You must not have used marijuana, CBD, or kratom recently.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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