Pregabalin and Lofexidine for Opioid Withdrawal
Part of Mental health clinical trials.
This study tests whether combining two medications, pregabalin and lofexidine, can help people stop using opioids by easing withdrawal symptoms. It's for adults who use opioids heavily and want to switch to a non-addictive blocker medication.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be 18 years or older.
- You must have used opioids on at least 20 of the last 30 days.
- You must be willing to take a medication that blocks the effects of opioids.
- You must have a stable place to live and not plan to move in the next 60 days.
- You cannot be pregnant, breastfeeding, or have certain serious mental health conditions.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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