Testing lemborexant for insomnia in people on buprenorphine
Treatments studied
Part of Brain & nervous system, Mental health clinical trials.
This study tests if the sleep medication lemborexant can help people with opioid use disorder who also have chronic insomnia. Participants must already be taking buprenorphine (Suboxone) for at least 4 weeks. The goal is to see if better sleep improves mood and reduces opioid use.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years old or older
- You are in treatment for opioid use disorder with buprenorphine (Suboxone or monthly shot) and have been on a steady dose for at least 4 weeks
- You have chronic insomnia (trouble falling or staying asleep most nights for at least a month)
- Your urine drug test shows you are taking buprenorphine and no illegal drugs (except marijuana)
- You do not have sleep apnea, narcolepsy, or other serious sleep disorders, and you are not currently taking other sleep medicines or sedatives
- You can complete online surveys and video visits using a computer or smartphone
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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