Clin2
NCT06007222Worth exploringRecruiting

No blood thinners after TAVI: a trial for heart valve patients

Aortic StenosisTAVI(Transcatheter Aortic Valve Implantation)AspirinDAPT(Dual Antiplatelet Therapy)SAPT(Single Antiplatelet Therapy)

Part of Heart & circulation clinical trials.

This trial is for people who have had a TAVI procedure to replace a narrowed heart valve, and it tests whether it is safe to skip blood thinners afterward. The goal is to find the best way to protect your health without unnecessary medication.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 4
Enrollment
400 people
Ages
20 years and older
Study type
Interventional

Who can take part

  • You are 20 years or older
  • You had a TAVI procedure through a leg artery
  • You do not need blood thinners (antiplatelet or anticoagulant drugs) for other health reasons
  • You are not on dialysis or have very low kidney function
  • You are not pregnant or planning to become pregnant
  • You are not allergic to aspirin

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT06818006Not yet recruiting· Phase 4
TAVI heart valve procedure without onsite heart surgery backup

This trial tests if a heart valve replacement procedure called TAVI can be safely done at heart centers that do not have a full heart surgery team available onsite. It is for people with severe narrowing of the aortic valve who are already planned for TAVI through the leg artery.

Edmonton, Alberta
NCT06472934Recruiting
Beta-blockers & TAVR study

This study tests whether continuing a beta-blocker (a heart medication) improves outcomes for people having a planned TAVR (a minimally invasive heart-valve replacement). It may help doctors decide whether to keep or stop this medicine after the procedure.

Graz
NCT06518317Recruiting· Phase 3
Short vs Long Blood Thinner Use After TAVI

This trial compares a short course versus a longer course of antiplatelet medicine (blood thinners) after a TAVI procedure for aortic stenosis. It aims to see which approach is safer and more effective.

Caen
NCT06168370Recruiting
Personalized blood thinners after TAVI vs. standard care

This trial tests whether a personalized plan for blood thinners after TAVI can reduce the risk of stroke or bleeding better than the current standard of one daily blood thinner. If you've had a successful TAVI and don't need specific other blood thinners, you might be able to join.

Nieuwegein
NCT05283356Recruiting· Phase 4
Ticagrelor or aspirin after heart valve replacement

This trial compares two blood thinners (ticagrelor and aspirin) to see which one works better at preventing blood clots after a less-invasive heart valve replacement (TAVI). It is for people with severe aortic stenosis who also have diabetes, heart disease, or artery disease.

Vigo, Pontevedra
NCT05493657Recruiting
Aspirin vs clopidogrel after TAVR valve procedure

This trial compares aspirin and clopidogrel (two blood-thinning medicines) after TAVR to see which is safer or more effective for preventing clots. You may be able to join if you recently had a TAVR for severe aortic valve narrowing and can follow the study plan.

Seoul

Hear when a new Aortic Stenosis trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.