Gel injection for painful lumbar discs
Part of Bones, joints & muscles clinical trials.
This trial tests a gel (HYDRAFIL-D) injected into painful discs in your lower back to see if it relieves pain. It's for people whose back pain hasn't improved with other treatments.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 22 and 85 years old.
- You have had back pain (more than leg pain) for at least 6 months due to degenerative disc disease in your lower back.
- You have one or two painful discs confirmed by a special X-ray test (discography).
- You have tried at least 6 months of non-surgical treatments (like physical therapy or pain meds) that didn't help enough.
- You have not had back surgery at the same level as your painful disc(s) in the past year, and no other surgeries that affect this trial.
- You can understand English and agree to follow the study schedule.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study tests if injecting a special cell therapy into a damaged spinal disc can reduce chronic low back pain. It is for people who have had low back pain for at least 6 months and haven't gotten enough relief from other treatments like physical therapy or pain medication.
This trial tests whether an injection placed into a painful neck disc can reduce long-lasting disc-related neck pain and numbness/arm pain when other non-surgical treatments have not helped. It looks at both how well it works and its side effects.
This study tests whether injecting a special disc material (nucleus pulposus allograft) into the damaged discs of your lower back can safely reduce pain and improve function. It's for people with long-term, moderate to severe low back pain from disc disease that hasn't gotten better with other treatments.
This trial tests a new drug called rhGDF-6 injected into the discs of your spine to help repair them. If you have had low back pain for at least 3 months despite trying other non-surgical treatments, and your MRI shows disc wear or changes, this study may offer a new option.
This trial is testing a treatment approach for people with long-lasting, painful worn-out discs in the lower back (and sometimes leg pain). It looks for people who tried common non-surgical options without enough relief and who may be headed toward a lumbar procedure.
This study compares two gels put on or into the painful disc area: an ethanol gel versus a steroid gel. It is for adults with long-lasting low back disc pain that did not improve with usual non-surgical care.
Hear when a new Degenerative Disc Disease (DDD) trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.