Trial of disc tissue injection for degenerative disc disease
Part of Bones, joints & muscles clinical trials.
This study tests an experimental treatment that injects donated disc tissue (called an allograft) into damaged discs in your lower back. It's designed for people with chronic low back pain from disc degeneration who haven't found relief from non-surgical treatments.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 22 and 85 years old.
- Your MRI shows moderate to severe disc wear in your lower back.
- You have had chronic low back pain for at least 6 months, and it hasn't improved with at least 3 months of non-surgical treatments.
- Your back pain is mainly centered in your lower back, without significant new leg weakness, numbness, or pain shooting down your leg (though some non-radiating leg pain might be okay).
- You must not have had any prior spine surgery or certain spine procedures in the last few months.
- You can't be pregnant, breastfeeding, or planning to become pregnant during the study, and if you could become pregnant, you must use reliable birth control.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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