Disc injection for chronic low back pain
Part of Bones, joints & muscles clinical trials.
This study tests whether injecting a special disc material (nucleus pulposus allograft) into the damaged discs of your lower back can safely reduce pain and improve function. It's for people with long-term, moderate to severe low back pain from disc disease that hasn't gotten better with other treatments.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 22 and 85 years old.
- You have moderate to severe disc degeneration seen on an MRI (a special scan).
- You have had low back pain (not shooting down your legs) for at least 6 months, and it hasn't improved with at least 3 months of treatments like physical therapy or medication.
- Your pain is severe enough to score between 40 and 90 on a 0-100 pain scale, and your disability from back pain is moderate (score 40-80 on a disability questionnaire).
- You haven't had surgery on your lower back, and you don't have metal implants or devices like a spinal cord stimulator in that area.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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