Injecting a growth factor for low back pain from worn discs
Treatments studied
Part of Bones, joints & muscles, Pain clinical trials.
This trial tests an injection of a protein called rhGDF-6 that may help repair damaged spinal discs and reduce low back pain. If you have chronic back pain from one or two degenerated discs, this treatment might be an option if other treatments haven't helped enough.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are at least 18 years old.
- You have had persistent low back pain for at least 6 months that is caused by a worn disc (diagnosed as discogenic pain).
- Your back pain is significant—enough that it bothers you a lot or requires medication.
- You have not had surgery on the specific painful disc before.
- You have not had any injections into the disc (like steroid shots) at that level before.
- You do not have severe nerve pain (numbness, tingling, or weakness) in your legs from a pinched nerve.
- You must be able to attend follow-up visits as scheduled.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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