Study of rhGDF-6 for chronic low back pain from disc degeneration
Treatments studied
Part of Bones, joints & muscles, Pain clinical trials.
This trial tests a new drug called rhGDF-6 injected into the discs of your spine to help repair them. If you have had low back pain for at least 3 months despite trying other non-surgical treatments, and your MRI shows disc wear or changes, this study may offer a new option.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must have low back pain that bothers you a fair bit or more, and have tried at least 3 months of non-surgical treatments like physical therapy or medication.
- Your MRI must show disc degeneration (grades 2-4) or signal changes at one or two discs in your lower back.
- You must be 18 or older and willing to come back for follow-up visits.
- You cannot have had any prior surgery on the painful discs or other treatments like steroid injections into those discs.
- You must not have certain other spine problems like a herniated disc pressing on a nerve, severe arthritis in the back joints, or cancer.
- You cannot be pregnant, breastfeeding, or planning to become pregnant during the first year of the study.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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