Study of RC148 for advanced solid tumors
Part of Cancer clinical trials.
This trial tests a new drug called RC148, both alone and combined with other treatments, for people with advanced solid tumors that haven't responded to standard therapy. It includes several groups for specific cancers (like non-small cell lung, cervical, stomach, and ovarian cancer) to see if RC148 can shrink tumors or slow their growth.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be 18 or older (for phase 1) or between 18 and 75 (for phase 2).
- You need to have a type of advanced solid tumor that has gotten worse after standard treatments, or you can't take standard treatments.
- The trial has different groups for specific cancers (non-small cell lung, cervical, gastric, lung adenocarcinoma, ovarian/fallopian tube/peritoneal) - you must have one of these.
- Your overall health should be good - you should be able to care for yourself and be out of bed at least half the day.
- You need to have at least one tumor that can be seen and measured on a scan, and your organs (like bone marrow, liver, kidneys) must work well enough.
- You cannot have certain conditions like active hepatitis or HIV, a recent live vaccine, or certain eye problems if in specific groups.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests a new drug called OCT-598, alone or with chemotherapy, for people with advanced solid tumors that have not responded to other treatments. It aims to see if the combination is safe and effective.
This study tests a new drug called RC288 to treat solid tumors (cancers that form lumps). Researchers want to see if it's safe and how well it works for people whose cancer hasn't responded to other treatments or has returned.
This study tests a new drug called RC278 for people with solid tumors that have not spread to the brain. It aims to see if the drug is safe and effective, and may be an option for those who are otherwise fairly healthy.
This trial tests a new drug combination (RC118 plus toripalimab/RC148) for people with advanced stomach or gastroesophageal junction cancer. It’s for those whose cancer has not responded to standard treatment and whose tumors have a specific protein called Claudin 18.2.
This trial tests a new drug (RC148) combined with standard chemotherapy as a first treatment for colorectal cancer that has spread or cannot be removed. The goal is to see if this combination works better than chemotherapy alone.
This trial tests a drug called RC48, alone or with envafolimab, for men with a specific type of advanced prostate cancer that has not responded to standard treatments. It aims to see if this combination can shrink tumors or slow disease progression.
Hear when a new Solid Tumor trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.