Nerve block plus steroid to prevent migraine return in 72 hours
Treatments studied
Part of Brain & nervous system clinical trials.
This trial tests whether adding a steroid pill (dexamethasone) to a nerve block can stop a migraine from coming back within three days. It's for people whose headache got much better after a nerve block.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have migraines as defined by standard headache guidelines.
- Your headache intensity dropped by at least 5 points after a nerve block, or you had a pain score of 0 to 2 after the block.
- The nerve block you received used a medication called bupivacaine 0.5%.
- You are not pregnant or do not have uncontrolled diabetes or a weakened immune system.
- You are not allergic to dexamethasone (a steroid) or currently taking steroids long-term.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study looks at whether a nerve block injection at the back of the head (called a greater occipital nerve block, or GONB) helps people with migraine when other preventive treatments haven't worked. It aims to find out which patients respond best to this treatment.
This study tests whether two types of nerve blocks (injections near the back of the head and neck) can improve sleep in people with chronic headaches. If you have ongoing headaches that haven't improved with other treatments, this might help you sleep better and reduce pain.
This study tests a nerve block injection at the back of the head to see if it can reduce migraines in people who also have headaches from overusing pain medication. It aims to provide a new treatment option for this difficult-to-treat condition.
This Phase 2 trial tests whether nerve block injections can reduce pain from episodic migraines. It may help some people who get frequent migraine attacks but are not also using certain migraine preventions or strong pain medicines.
This Phase 3 trial tests whether repeated injections can reduce attacks of chronic cluster headache. It may help people who have frequent, consistent attacks and can track them closely during the study.
This study compares two common treatment approaches for primary headache (headaches not caused by another condition) to see which works better and faster. If you have a recent headache with significant pain, you might be able to join.
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