Dexamethasone and metoclopramide versus over-the-counter pain relief for primary headaches
Part of Brain & nervous system, Pain clinical trials.
This trial compares two treatment approaches for primary headaches (migraines, tension headaches, cluster headaches with no underlying serious cause). One group receives dexamethasone (a steroid to reduce inflammation) plus metoclopramide (to help with nausea and speed medication absorption), while the other receives common over-the-counter pain relievers. The goal is to see which approach works better and faster.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 60 years old
- Your headache started within the last 72 hours
- Your pain level is at least 5 out of 10 on a pain scale
- Your headache is primary (no underlying serious condition like infection, tumor, or stroke causing it)
- You have not taken any steroid medications in the past 48 hours
- You have no history of liver or kidney problems, stomach ulcers, or bleeding in the digestive system
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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