Azacitidine plus gilteritinib for FLT3-mutated AML
Treatments studied
Part of Blood & lymphatic, Cancer clinical trials.
This trial tests whether adding an oral chemotherapy pill (azacitidine) to the targeted drug gilteritinib helps people whose FLT3-mutated AML came back or didn't respond after their first treatment. The goal is to see if the combination is more effective than gilteritinib alone.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must have AML with a FLT3 gene mutation.
- Your AML must have come back (relapsed) or not responded (refractory) to your first treatment. You cannot have had more than one prior treatment.
- You cannot have taken gilteritinib or oral azacitidine before.
- Your kidneys and liver need to be working well, and your heart function should be at least 45%.
- You must be able to take pills by mouth and be covered by French health insurance.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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