Testing tizanidine to help reduce opioids after surgery
Part of Mental health, Pain clinical trials.
This study tests whether adding a low-dose muscle relaxant (tizanidine) to your pain plan after surgery can help you safely lower your opioid use. It's for people who have been on long-term opioids and are having surgery at specific hospitals.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 75 years old
- Your surgery is at Stanford, Brigham and Women's (Harvard), Atrium Health Wake Forest Baptist, or University of Kansas Medical Center
- You've been taking opioids (like oxycodone or morphine) for at least 60 days in the last 6 months
- You have some extra concerns about pain or medication use (like needing pills to sleep, taking more than prescribed, or using tobacco daily)
- You are not currently taking tizanidine or certain other medications (your study team will check this)
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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