Tizanidine before leg surgery for better pain and sleep

This study tests whether giving ketamine before or during surgery can reduce pain afterward. It is designed for adults with higher body weight who also have certain health conditions like well-controlled diabetes or blood pressure.

This study looks at whether giving sedation (medicine to help you relax) during spinal anesthesia can reduce back pain after surgery. It's for people having certain types of surgery on their lower abdomen or legs.

This study tests whether adding a low-dose muscle relaxant (tizanidine) to your pain plan after surgery can help you safely lower your opioid use. It's for people who have been on long-term opioids and are having surgery at specific hospitals.

This trial tests a medicine called tizanidine to see if it helps with pain after pelvic surgery. It may help reduce the need for opioids.

This trial tests whether tizanidine, a muscle relaxant, helps reduce pain and improve shoulder function after arthroscopic surgery for rotator cuff tears. It may be an option if you have persistent shoulder pain and weakness despite prior treatment.

This study tests two medications given through an IV (dexmedetomidine and midazolam) to see which one better prevents shivering during and after leg surgery done under spinal anesthesia. If you're having this type of surgery, participating might help you feel more comfortable and avoid the stress of shivering.