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NCT06040541Possibly a fitRecruiting

Study of RMC-9805 for KRAS G12D solid tumors

Non-small Cell Lung Cancer (NSCLC)Colorectal Cancer (CRC)Pancreatic Ductal Adenocarcinoma (PDAC)Advanced Solid Tumors

Treatments studied

Part of Cancer, Digestive system, Hormones & metabolism, Lungs & breathing clinical trials.

This trial tests an experimental pill (RMC-9805) for people with solid tumors that have a specific KRAS G12D mutation. It's for those who have already tried other treatments and need new options.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 1
Enrollment
604 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • Your tumor must have a specific KRAS G12D mutation (a genetic change).
  • You have already tried at least one standard treatment for your cancer, and it stopped working or caused side effects you couldn't tolerate.
  • You are in good physical condition (able to do normal daily activities).
  • Your organs (like kidney, liver, and bone marrow) are working well enough.
  • You cannot have active cancer that has spread to the brain or spinal cord, or have trouble swallowing pills.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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