Clin2
NCT06041776Possibly a fitRecruiting

Befotertinib after surgery for early-stage lung cancer with EGFR mutation

Non-Small Cell Lung CancerEGFR Sensitive MutationAdjuvant Therapy

Part of Cancer, Lungs & breathing clinical trials.

This trial tests if a targeted therapy pill (befotertinib) can lower the chance of cancer coming back after surgery for non-small cell lung cancer that has a specific EGFR mutation. You may be eligible if your tumor was completely removed and you have stage IB to IIIB disease.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 3
Enrollment
570 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You have been diagnosed with non-small cell lung cancer (mainly a type called adenocarcinoma) that has a common EGFR mutation (exon 19 deletion or L858R).
  • Your cancer was stage IB, II, IIIA, or IIIB (T3N2M0) and was completely removed by surgery, with no cancer cells left at the edges.
  • You are at least 18 years old, and your surgery was 4 to 10 weeks ago with full wound healing.
  • You have not had brain metastases and you do not have any other active cancer or serious heart or lung conditions.
  • You are willing to use effective birth control during the study and for 3 months after treatment ends.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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