Clin2
NCT06041789Possibly a fitRecruiting

Does a memory medication affect bone health?

Osteoporosis

Treatments studied

Part of Bones, joints & muscles, Hormones & metabolism clinical trials.

This study looks at whether a common memory medication (called donepezil) can also help keep your bones strong. If you have memory problems and are willing to start this medication, you might be able to join.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 2
Enrollment
45 people
Ages
50 years and older
Study type
Interventional

Who can take part

  • You must have been diagnosed with some form of memory or thinking problem.
  • You need to be willing to start a new medication for your memory or thinking.
  • Women over 55 (or under 55 if you've stopped having periods for at least a year) and men over 50 are eligible.
  • You should not be currently taking a memory medication like donepezil for more than 3 months.
  • You must not have certain heart conditions (like slow heartbeat or heart block) that prevent taking donepezil.
  • You should not be on any bone-strengthening medications (like bisphosphonates) or have had certain fractures, surgeries, or medical conditions.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07329543Not yet recruiting
How the body's age affects bone-strengthening treatment for osteoporosis

This study looks at how the natural aging of the body might affect how well bone-strengthening medications work for osteoporosis. If you are about to start one of these medications, the study will track your bone density over time to see how your response may differ based on your 'biological age.'

NCT06118905Recruiting· Phase 4
Osteoporosis medication to preserve muscle in seniors

This study tests whether an osteoporosis medication can help preserve muscle strength in older adults who live in senior facilities. It's for people age 65+ with fragile bones or low bone density who are at risk for falls and fractures.

Pittsburgh, Pennsylvania
NCT07616401Recruiting
Bone-Strengthening Drugs and Biomarkers in Postmenopausal Osteoporosis

This study tests two injectable medications (romosozumab and abaloparatide) that help strengthen bones in women after menopause. Researchers will also look at blood markers to understand why some women respond better to treatment than others.

Miano, Lombardy
NCT06938152Recruiting· Phase 4
Comparing two bone-strengthening drug schedules for osteoporosis

This trial tests whether switching between two medications (Romosozumab and Denosumab) using a cycle or sequence schedule works better for improving bone density in postmenopausal women with severe osteoporosis. It aims to find the most effective treatment plan.

Taipei
NCT04661280Recruiting· Phase 3
Donepezil compared with non-drug care for Alzheimer’s

This trial compares donepezil (a medicine for Alzheimer’s symptoms) against a non-drug treatment plan. It aims to see which approach helps people with Alzheimer’s who still have measurable thinking ability and specific Alzheimer’s test results.

Paris
NCT05764733Recruiting· Phase 4
How bone exercise, alendronate, and diet affect bone strength

This trial studies whether doing a structured bone-focused exercise program, taking alendronate (a medication that slows bone loss), and making a calorie-reducing diet can improve bone strength in people with low bone density. It also compares different combinations to see what helps most and is safest for you.

Aurora, Colorado

Hear when a new Osteoporosis trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.