Severe infant asthma and the lung microbiome study
Treatments studied
Part of Immune system & allergy, Lungs & breathing clinical trials.
This study looks at the bacteria (microbiome) in the airways of infants under 2 years old with severe asthma. It aims to understand how these bacteria might affect the disease.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Your baby must be less than 24 months old.
- Your baby must be diagnosed with severe asthma by a pediatric lung doctor.
- Your baby is scheduled for a daytime hospital visit for testing, including a bronchoscopy (a thin tube with a camera to look at the airways).
- You agree to have your baby take part and sign a consent form.
- Your baby was not born before 32 weeks of pregnancy.
- Your baby does not have a heart defect that causes extra blood flow to the lungs.
- Your baby does not have another chronic lung disease (like cystic fibrosis or bronchiolitis obliterans).
- Your baby has not taken antibiotics in the last week, or is not currently on antibiotics.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study looks at whether differences in the body’s bacteria (in the gut and/or airways) can help predict which toddlers with asthma may develop a more severe form. It may help doctors identify children at higher risk earlier so they can be monitored more closely.
This study looks at how the gut and lungs affect breathing problems in children. It compares samples from children with and without respiratory illnesses to understand why some children get sicker than others.
This study looks at the tiny germs in your airways (airway microbiota) to better understand different asthma “types” and what might drive symptoms. It may help researchers find more personalized approaches to asthma care by learning how lung bacteria relate to your asthma features.
This study collects samples (like fluid from the lungs) during a planned bronchoscopy to look for new ways to understand and predict children's breathing problems. It might help if your child already needs this procedure for a medical reason.
This study looks for biological “markers” that may help explain why asthma starts and how it changes over time in children. It may help your child’s doctors understand asthma better, especially for diagnosis or tracking.
This study follows children with wheezing (in younger kids) or doctor-diagnosed asthma (in older kids). It aims to better understand asthma and related breathing problems and how they develop over time.
Hear when a new Asthma in Children trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.