Immune cell therapy for high-risk solid tumors in children and young adults
Part of Cancer, Immune system & allergy clinical trials.
This trial uses a patient's own tumor-fighting immune cells (TILs) to treat high-risk solid tumors outside the brain in children and young adults. It has two parts: first, a tumor sample is collected during surgery, and then the immune cells are grown in a lab and given back to the patient to attack the cancer.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Aged 1 to 21 years for the first part (no upper age limit for the second part if enrolled in the first part)
- Have a high-risk solid tumor outside the brain, such as neuroblastoma, Ewing sarcoma, osteosarcoma, or other listed types
- Must be having surgery to remove or biopsy the tumor as part of standard care
- Weight at least 11 pounds (5 kg) when starting the treatment part
- Able to perform daily activities with minimal help (Karnofsky/Lansky score of 60% or higher)
- Good organ function: healthy blood counts, liver, kidneys, heart, and lungs
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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